Compliance updated on Jun 19, 2026 Screened by AAOIFI-Certified Shariah Advisor & Auditor

Financial data updated nightly

Prime Medicine, Inc

PRME ✗ NOT COMPLIANT ☆ Track — members

Nasdaq · Healthcare · Biotechnology & Medical Research ·

USA Small Cap Analyst: BUY

Last Close

$3.70

▼ -0.27%

Market Cap $671.09M · Vol 539.55K

Key Metrics

P/E Ratio

N/A

FWD: N/A

Market Cap

$671.09M

Small Cap

Div Yield

N/A

EPS Growth

+27.66%

YoY

RSI (14)

62.80

Momentum

Beta

2.34

vs Market

52W High

$6.94

46.65% below

52W Low

$2.68

38.32% above

Volume

539.55K

Avg 753.98K

P/B

5.18

Price-to-book

ROE

-146.81%

Return on equity

Free Float

76.33%

Public shares

Shariah Compliance8 STANDARDS

✗ Prime Medicine, Inc (PRME) stock is currently not Shariah compliant

AAOIFI—
Dow Jones Islamic (DJIM)—
FTSE Shariah—
MSCI Islamic—
S&P Shariah—
Al Rajhi—
Alinma—
Albilad—

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Which standards does PRME pass?

The full report shows the verdict under each of the 8 major Shariah standards, with the business-activity and financial-ratio screens behind every one.

Do I need to purify my investment?

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Historical Returns

+2.49%

+24.16%

+6.63%

-10.19%

YTD

+6.63%

+8.82%

-69.17%

N/A

Financials & Valuation

TTM · Annual

Total Revenue	$4.63M
Net Income	$-201,142,000.00
Revenue Growth (YoY)	+3.50%
Gross Margin	100.00%
Operating Margin	-4,498.06%
Net Profit Margin	-4,342.44%
ROE	-146.81%
ROA · ROIC	-62.83% · N/A

P/E Ratio	N/A
Forward P/E (FY1)	N/A
PEG Ratio	N/A
P/S	111.44
P/B	5.18
P/FCF	N/A
EPS Growth	+27.66%
Outstanding Shares	181.38M

Technical Indicators

50-Day SMA	$3.39
200-Day SMA	$3.55
RSI (14)	62.80
Beta	2.34
52-Week High	$6.94
52-Week Low	$2.68

Volume Today	539.55K
Avg Daily Volume (30D)	753.98K
Relative Volume	0.72x
Volatility (10D)	72.64
Volatility (30D)	76.11
Free Float	76.33%

Analyst Consensus

BUY

Current Price $3.70

Mean Target $6.93

52W Low$2.68 52W High$6.94

Current

Target

$2.68 $6.94

Current Analyst target

+87.16% upside potential · 14 analysts

Identifiers

ExchangeNasdaq

FIGIBBG011RT3R64

ISINUS74168J1016

CountryUnited States of America

Sub-IndustryBio Therapeutic Drugs

Earnings DateNov 5, 2026

TypeStocks

Instrument TypeORD Ordinary Share

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Company Profile

Prime Medicine, Inc. is a biotechnology company focused on developing genetic medicines designed to provide durable, and potentially curative, treatment options for patients with diseases driven by defined genetic alterations, acquired cellular dysfunction, or dysregulated gene expression. Its gene editing technology enables targeted modifications to genomic deoxyribonucleic acid (DNA) without introducing double-stranded breaks. The Company pipeline includes wholly owned in vivo programs targeting liver genetic diseases Wilson Disease, Alpha-1 Antitrypsin Deficiency (AATD) as well as early-stage discovery efforts in Cystic Fibrosis (CF). The PM359 is an ex vivo prime editing program designed to correct the GT mutation in the NCF1 gene, the most common cause of Chronic Granulomatous Disease (CGD). This program provides validation of prime editing in human cells. The Wilson Disease is a rare autosomal recessive disorder caused by loss-of-function mutations in ATP7B.